tyrosine kinase

Conclusion STI 571 could induce leukemia cells of ANLL into terminal differentiation by inhibiting c-kit tyrosine kinase.

结论STI571对急性非淋巴细胞白血病原代细胞有诱导向同系终末分化的作用,对c-kit酪氨酸激酶有明显的抑制作用,且与药物浓度相关.

Conclusion High affinity binding is required for efficient endocytosis which is not affected by the tyrosine kinase phosphorylation.

结论有效的胞吞需要高亲和结合力的功能受体存在，且胞吞过程不涉及酪氨酸激酶磷酸化；

Expression of Fams-like tyrosine kinase 3 in five cell lines with acute myelocytic leukemia and detection of internal tandem duplication mutation

五种急性髓细胞白血病细胞株FAM样酪氨酸激酶3表达及其短状串联重复突变检测

Expression of neurotrophin 3 and tyrosine kinase C in Hirschsprung's disease and its significance

先天性巨结肠神经营养因子-3、酪氨酸激酶C的表达及其意义

Trk ( tropomyosin-related kinase) is an important tyrosine kinase family which locates on cell membrane. It exerts pivotal roles in neuron survival, proliferation, differentiation, migration, apoptosis, learning and memory.

Trk（tropomyosin-related kinase，原肌球蛋白相关激酶）是细胞膜表面的一类重要酪氨酸激酶，其在神经细胞的存活、增殖、分化、迁移、凋亡以及学习和记忆等高级功能中都扮演着关键角色。

Is PDGF tyrosine kinase inhibitor effective in pancreatic cancer?

PDGF受体酪氨酸激酶抑制剂在胰腺癌中是否有作用?

Establishment of homogeneous time-resolved fluorescence immunoassay for high throughput screening of protein tyrosine kinase inhibitors

用于蛋白酪氨酸激酶抑制剂高通量筛选的均相时间分辨荧光免疫方法的建立

Each of the four mammalian neurotrophins has been shown to activate one or more of the three members of the tropomyosin-related kinase ( Trk) family of receptor tyrosine kinases ( TrkA, TrkB and TrkC).

每种神经营养素，可以激活受体酪氨酸激酶原肌球蛋白相关激酶家族中的三个成员（TrkA、TrkB、TrkC）中的一个或多个。

All these actions VEGF are mediated by receptor tyrosine kinase , vascular endothelial growth factor receptor ( VEGFR ).

所有这些作用都是通过血管内皮生长因子 受体 信号转导通路实现的.

Genistein, the tyrosine kinase inhibitors, plays the effect by an inhibition of tyrosine phosphorylation.

Genistein 是酪氨酸激酶的非特异性抑制剂, 通过抑制酪氨酸的磷酸化而发挥作用.

Objective To investigate the expression of tyrosine kinase ETK and its significance in lung cancer tissues.

目的：探讨酪氨酸激酶ETK在肺癌组织中的表达及意义。

Through coupling and cytoplasmic tyrosine kinase JAK activating, Leptin receptor realizes signal transduction.

瘦素受体通过偶联和激活胞质酪氨酸激酶JAK（主要是JAK-1和JAK-2）而实现信号转导。

Tissue distribution and signal transduction of Tec tyrosine kinase in rats

Tec酪氨酸蛋白激酶的大鼠组织分布及参与的信号途径

CONCLUSION: CD117 can be regard as the related tumor antigen of MM, and may be a valuable marker in the use of tyrosine kinase selective inhibitors, which inhibit the signal conduct to the target.

结论CD117可作为MM的肿瘤相关抗原，也可作为靶向信号转导抑制剂酪氨酸激酶选择性抑制剂应用的有价值的标志。

Insulin receptor tyrosine kinase activity and substrate 1 ( IRS-1) expression in human myometrium and leiomyoma

人体子宫肌层和平滑肌瘤组织中胰岛素受体酪氨酸激酶活性与底物1（IRS-1）的表达

Objective Study the expression of Bruton ′ s tyrosine kinase ( BTK) in primary hypogammaglobulinemia.

目的研究临床诊断为原发性低丙种球蛋白血症Bruton′s酪氨酸激酶（BTK）表达及意义。

Objective To assess the role of tyrosine kinase receptor flk 1 in the development of hypoxic pulmonary vascular remodeling.

目的评价酪氨酸激酶受体flk-1在低氧性肺血管重建中的变化和作用。

conclusion: chinese prescription of fujian tablets can predominantly enhance the expression of tyrosine kinase receptor b, the positive regulating factor in nerve growth factor, in the brain of mcao rats.

结论：中药复方复健片可显著增强大脑中动脉闭塞大鼠脑内神经生长因子正性调控因子酪氨酸激酶受体B的表达。

The effect of simultaneously blocking target epidermal growth factor receptor tyrosine kinase and cyclooxygenase-2 on the growth of NPC cell

靶向联合阻断表皮生长因子受体和环氧化酶-2信号通路影响鼻咽癌细胞生长的研究

Chapter I: FLZ attenuats neuroinflammation and protects dopaminergic neurons through inhibiting Src tyrosine kinase.

第一章：FLZ通过抑制Src酪氨酸激酶减弱神经炎症并保护多巴胺能神经元。

The expression of tyrosine kinase receptor B in the brain of MCAO rats was observed by immunohistochemical method.

免疫组化法观察大脑中动脉闭塞大鼠脑内酪氨酸激酶受体B的表达。

Objective To investigate the effects of Src tyrosine kinase in the development of cerebral vasospasm after subarachnoid hemorrhage. To observe the therapeutic effect of PP2, an inhibitor of src, on cerebral spasms.

目的探讨酪氨酸激酶（Src）在蛛网膜下腔出血（SAH）后脑血管痉挛（CVS）中的作用和机制，以及应用Src抑制剂PP2对脑血管痉挛的治疗作用。

FGFR 3, a member of polypeptide growth factor family, is a tyrosine kinase receptor.

FGFR3是这一多肽类生长因子的家族成员之一, 它是一种酪氨酸激酶受体.

Results K562-ibE cell was obtained. Expression of the BCR/ ABL and c-ABL protein tyrosine kinase activity of harvested K562-ibE cells were markedly inhibited.

结果获得表达胞内抗体基因的细胞模型：K562－ibE，其靶蛋白酪氨酸激酶活性明显受抑。

Comparative study of insulin receptor tyrosine kinase and its endogenous substrate in transformed and untransformed K-562 cells

转化前后K-562细胞胰岛素受体酪氨酸蛋白激酶活性及内源性底物的研究

Lymphocyte-specific protein tyrosine kinase is a novel risk gene for Alzheimer disease

淋巴细胞特异蛋白酪氨酸激酶是阿尔茨海默病的一个新危险基因

Conclusion: Genistein can decrease the vascular tone in femoral vascular bed with the underlying mechanism that involves tyrosine kinase inhibition and NO release.

结论：GST降低股动脉血管床的血管张力，其机制与酷氨酸激酶抑制和NO释放有关。

The inhibitor of VEGF receptor tyrosine kinase was introduced in detail.

详细介绍了vegf受体酪氨酸激酶抑制剂的研究进展.

The non-receptor tyrosine kinase c-Abl in mammalian is the homeotic gene of v-abl which is proto-oncogene of Abelson in murine leukemia virus; it belongs to the family members of the Abl, and can be widely expressed in mammalian cells.

非受体酪氨酸激酶c-Ab1的在哺乳动物细胞内的编码基因c-abl是v-abl的同源基因，v-ab1是Abelson鼠白血病病毒原癌基因。c-Ab1蛋白属于非受体酪氨酸激酶Abl家族的成员，在哺乳动物细胞中能够广泛表达。

Association between the polymorphisms of lymphocyte-specific protein tyrosine kinase ( LCK) gene and AD

淋巴细胞特异性酪氨酸蛋白激酶基因多态性与阿尔茨海默病的相关性研究